DU turned a 6-point halftime lead into a 15-point advantage over the first eight minutes of the first half thanks to strong rebounding and a defense that forced the Terriors into five turnovers.
Leading by 11 with 8:03 to play, The Big Red would go on a 14-1 run over a three minute stretch, effectively putting the game out of reach.
Hale was 8-for-16 from the field and 7-of-8 at the free throw line for 23 points. Akpapunam followed with a career-high five 3-pointers and 17 points. He was 5-of-7 from the field in 22 minutes.
Briggs King added nine points and four rebounds while Darius White chipped in eight points off the bench. Another first-year who had a big night off the bench was Patrick Keller. He grabbed a game-high nine rebounds, with five coming on the offensive glass, in 19 minutes.
Alan Sheppard and Aaron Stefanov led Hiram with 11 points.
Denison held a 35-32 edge on the glass while committing just 11 turnovers. Hiram turned the ball over 13 times while shooting 34 percent from the field. The Big Red hit on 43 percent of its shots and was excellent from long range, going 10-for-22 from beyond the arc.
Denison improves to 3-2 overall and 1-0 in the North Coast Athletic Conference while Hiram drops to 1-1. DU will hit the road on Saturday (Dec. 1) for a 3 p.m. tip-off at Wabash College in Crawfordsville, Ind.